Circular-Dichroic Spectra of Vasopressin Analogues and Their Cyclic Fragments

Graphical analysis of circular dichroic spectra distinguishes between two-state and gradual alterations in DNA conformation.

A simple graphical method is proposed to distinguish between two-state and gradual alterations in DNA conformation from circular dichroic spectra. The method is advantageous particularly to identify two-state conformational isomerizations which exhibit low degree of cooperativity. The usefulness of the method is illustrated on the examples of two synthetic DNA molecules which isomerize due to t...

A new basis for interpreting the circular dichroic spectra of proteins.

Experimental circular dichroic (CD) spectra of three proteins have been combined with estimates of the content of peptide-chain structural modes obtained from x-ray diffraction studies of the same proteins. Solution of the simultaneous equations at a series of wavelengths permits the construction of a CD spectrum for each of three structural modes: alpha-helix, beta-structure, and the so-called...

Analogues of Cyclic Amp and Their Physiological Response

Sutherland's second messcngr model and the intracellular cAMP-system is presented. The key-points of its manipulation by externally applied compounds are discussed. They form the guidelines for development of chemical analogues of the cAMP molecule effective on phosphodiesterases and protein kinases. Special attention is devoted to their influence on glycogenolysis, steroidogenesis, lipolysis, ...

architecture and engineering of nanoscale sculptured thin films and determination of their properties

چکیده ندارد.

A circular dichroic study of cu(II)-ribonuclease complexes.